What is cannabidiol? The effect on the human body

What is cannabidiol? The effect on the human body

Cannabidiol (short form "CBD") is a hardly psychoactive cannabinoid, which is obtained from female hemp. The medical effect against muscle cramps, inflammations, psychological fears and nausea has been investigated.

In this article we would like to explain how cannabidiol affects the human body. In this context, we take a closer look at the chemical composition, we look at the active substances in detail and finally we look at the spectrum of activity of this substance known so far.

Therefore, if you are looking for in-depth information about the substance, read this article carefully to gain a deeper understanding of the subject.

Chemical composition and mode of action of cannabidiol

The medical use of cannabidiol can be traced back to a long tradition. According to different statements the hemp extract was already used 5000 to 10,000 years ago for medical purposes.

Extensive scientific research has increasingly been carried out in the recent past. Within the framework of these tests, 489 components contained in the hemp plant have already been detected.

The components of the hemp plant

The ingredients included 70 phytocannabinoids. In this context, tetrahydrocannabinole, known to most as THC, cannabidiol (CBD), cannabinole (CBN) and finally cannabigerole (CBG) were extensively investigated.

In this context, we distinguish between the psychoactive components such as THC, which occurs in high doses in cannabis, and the non-psychoactive components such as cannabidiol, which binds to the receptor system and can contribute to the alleviation of physical and mental pain.

The last point in particular is dealt with in more detail in this article, in order to clearly emphasise that the substance is not a narcotic that impairs the consumer in any way in everyday life.

The substance is regarded in the health industry as an ingredient which is not psychoactive and therefore combines all the advantages of the hemp plant without causing a state of intoxication.

Components of CBD

The Endocannabinoid System

The endocannabinoid system is made up of fatty acids which are linked to the nervous system and influence the respective receptors there.

This refers to CB1 and CB2 receptors, which are activated by cannabinoids and ultimately produce various effects, which we describe in detail in this article.

The difference between THC and CBD

The effect of THC and CBD on our receptors is often confused. For this reason, we would like to emphasize the crucial difference at this point, so that the misbelief disappears that the active ingredient works like marijuana.

In science, THC is referred to as a CB1 receptor antagonist. This means that THC binds to the CB1 cannabinoid receptors and ultimately stimulates them. This produces the effect known from marijuana consumption.

This is accompanied, for example, by greater sensitivity or increased consumption of food.

The cannabidiol substance, on the other hand, has other effects on our receptors. Compared to THC, the binding capacity of this substance is minimal.

Thus, CB1 receptors are not suppressed and, as a result, the possible negative effects of cannabis, such as excessive sensitivity and anxiety disorders, are eliminated.

THC vs CBD: The most important points in a nutshell

  • THC affects consciousness and causes a state of intoxication that can last for several hours and be detrimental to the psyche.
  • CBD does not cause a state of intoxication that clouds the psyche and possibly leads to anxiety and long-term consequences.
  • THC increases appetite, leading to the "eating attacks" known to marijuana consumers.
  • CBD, on the other hand, tends to reduce the feeling of hunger.
  • THC use, especially on a more regular basis, can contribute to the development of secondary damage such as psychosis, which can reduce the quality of life of those affected.
  • CBD, on the other hand, helps to calm both body and mind. This in turn can support the relief of pain.

CBD must be clearly distinguished from THC

The 18 advantages of cannabidiol

Analgesic

CBD is believed to help relieve pain and migraine. It is also currently being investigated in more detail whether the substance can contribute to alleviating menstrual cramps.

Anti-flammable

If you regularly struggle with acute or chronic inflammation in your body, CBD could help you to noticeably reduce it. [1]

anorectic

It is often reported that the substance can have a supportive effect on diets.

If you want to reach your ideal weight, then taking it may help you to reduce your appetite and avoid hunger attacks.

Antiemetic

Those who are often plagued by nausea could alleviate their symptoms with CBD. [1]

However, since there are no studies on how the substance affects pregnancy, it should not be used.

Anti-kinetic

A wrong diet can lead to intestinal problems, which are accompanied by acute or chronic symptoms. Scientists assume that the active ingredient soothes the intestines and thus helps to reduce unwanted symptoms. [3]

Anxiolytic

Depression and anxiety are an increasing phenomenon in modern society. A large number of people are affected. Here, too, CBD can help by successfully combating symptoms associated with anxiety and depression. [1]

Neuroleptic

Even with severe mental illnesses such as delusions, loss of reality or schizophrenia [2], CBD can alleviate symptoms and support normal everyday life.

Antiepileptic

Although not yet clearly proven, some studies suggest that the substance also helps against epileptic seizures, or at least reduces them. [1]

Antispasmodic

Office workers in particular often suffer from tension in the back muscles.

Since CBD has a relaxing effect, muscle tension and cramps can be effectively reduced.

Antiinsomic

You feel stressed a lot, so it's hard for you to fall asleep? Cannabidiol calms the body and could help people with problems falling asleep to relax and develop a healthy sleep routine that has a positive effect on their quality of life.

immunusupressive

It is assumed that the active ingredient can alleviate the symptoms of irritable skin. Meaningful scientific studies are currently being conducted and promise positive results.

Antidiabetic

It is currently being investigated whether the active substances also help with diabetes. Some scientists at least assume that this is the case. Valid results on the part of science are to be expected shortly.

neuroprotective

Dementia and Alzheimer's often occur with age and can lead to a noticeable change in personality. In this context, the substance could act as a preventive measure to combat dementia and Alzheimer's disease.

Antipsoriatric

Psoriasis and similar skin diseases may be treated with the active ingredients. The substance helps the skin to regenerate and contribute to a healthy appearance again.

In the future, however, further investigations will be carried out in this regard, which will provide a final result.

antiischemic

Cannabidiol can reduce the reduced blood flow to the tissue and help to regulate it successfully when taken regularly.

Antibacterial

It is believed that cannabidiol is effective against bacteria. However, the results of scientific studies are still pending in this context.

antifungal

Annoying fungal infections (e.g. athlete's foot) could possibly also be reduced with the active ingredients contained. The oil is simply applied to the appropriate areas.

antiproliterative

It is assumed that the Active ingredient cannabidiol reduces cancer growth. However, there are still no valid study results on this subject, and scientists are investigating the effect on cancer growth.CBD can promote health

Is cannabidiol legal?

In recent years, numerous scientific studies have been carried out to prove whether the substance is a legal means of successfully combating different types of complaints. Some of them we have linked to you at the end of the article, so that you can inform yourself additionally.

Further studies are underway to focus on the legality and appropriateness of cannabidiol. The success of these studies is increasingly underpinning the efficacy of the active ingredients.

For this reason, CBD is legal in many European countries, although there is still no uniform legal basis.

However, the number of legal companies and websites specialising in the production and distribution of the substance shows that there is no antipathy on the part of the judiciary and that there is a high demand from consumers.

Are there any side effects of Cannabidiol?

The numerous studies conducted showed that in most cases the substance can be consumed without consequences. Especially with small amounts (e.g. a few drops a day), side effects are almost impossible.

Cannabidiol is well tolerated even with a high consumption of 150mg daily. As some studies are still ongoing, scientists point out that 100% results may be available at the end of these studies.

So far only the combination of cannabidiol with other drugs, which could possibly lead to side effects, should be considered.

Cannabidiol and the Taking of Medications

It is assumed that possible side effects may occur in combination with antidepressants, beta-blockers or immunomodulators. The latter are pharmacological substances that serve to strengthen the natural immune reactions.

Taking steroids, anesthetics and benzodiazepines may also cause side effects. Benzodiazepines are active substances that have a muscle relaxing, anxiety-relieving or calming effect.

Here too, however, science is working meticulously to find out whether side effects can occur in combination with the active substance.

How is cannabidiol consumed?

Cannabidiol can be used as extract, flower, tea, as CBD crystal or liquid or as oil. Oils that can be purchased on websites are particularly popular at present. The basic trend is that oils will prevail on the market because they can be used in different ways.

Taking cannabidiol as oil

For example, the oils can be applied to the skin to help combat skin diseases.

Pay attention to the quality of cannabidiol

The number of websites offering products containing cannabidiol is growing rapidly. In this context, it is important to find out which companies manufacture and distribute high-quality products.

In this context, many dealers lack a seal that emphasizes quality and purity.

If you do not find such a seal at the time of purchase, find out whether the desired product has also been tested in the laboratory and produces the corresponding effect. After all, you don't want to waste your money pointlessly.

When is cannabidiol suitable for me?

Finally, you may ask yourself whether the use of cannabidiol makes sense for you. For this reason, we have listed the most common reasons why people decide to consume CBD in the following.

Application examples of our readers:

  • To alleviate stress against challenges in private and professional everyday life.
  • Against chronic sleep problems, which have a negative effect on the quality of life.
  • For chronic depression and anxiety, which are to the detriment of one's own performance.
  • For concentration disorders at work or during studies.
  • The substance is often used for chronic pain, muscle tension or cramps.
  • As a substitute, if they are dependent on THC for health reasons.
  • Recurring migraines, which restrict her in her everyday life.
Note: In this article we report on prescription cannabis, prescription CBD or over-the-counter or legal CBD. This Article does not make any proposal as to the possible purpose of the proposal and is for information and education purposes only. Promises of healing and benefits are excluded.

Sources:

[1] R. Mechoulam, M. Peters, E. Murillo-Rodriguez, L. O. Hanus: Cannabidiol - recent advances. In: Chemistry & Biodiversity. 4, 8, 2007, S. 1678–1692

[2] A. W. Zuardi, J. A. Crippa, J. E. Hallak, F. A. Moreira, F. S. Guimarães: Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. In: Braz. J. Med. Biol. Res. (Review) 39 (4), April 2006, p. 421-429

[3] G. Esposito, D. D. Filippis, C. Cirillo, T. Iuvone, E. Capoccia, C. Scuderi, A. Steardo, R. Cuomo, L. Steardo: Cannabidiol in inflammatory bowel diseases: a brief overview. In: Phytotherapy research : PTR. Volume 27, Number 5, May 2013, P. 633-636